Utdrag från
studien:
"The two main objectives of antibody testing are to check if the animal (i) has been vaccinated according to recommendations, and (ii) has developed an adequate humoral immune response. Previous studies in conventional pet dogs show that the antibody response is influenced by vaccine product used, number of vaccine doses in the primary immunisation schedule, interval between vaccination and blood sampling, age, size and breed of the dog (Cliquet and others 2003, Mansfield and others 2004, Kennedy and others 2007, Jakel and others 2008). However, taking these aspects into consideration, more than 85 per cent of vaccinated dogs achieve an adequate immune response after one dosage of rabies vaccine (Fooks and others 2002, Council of Europe 2008, Van de Zande and others 2009, Berndtsson and others 2011). Several studies report that the interval between vaccination and testing will affect the proportion of dogs with titres above 0.5 IU/ml since peak antibody values are seen four weeks to six weeks postvaccination (Cliquet and others 2003, Mansfield and others 2004, Jakel and others 2008). Therefore analysis was restricted to only those dogs that had been vaccinated four months to six months before sampling to standardise with the control group (Berndtsson and others 2011), and the difference between imported rescue dogs and owned Swedish dogs was statistically significant. Only 45.5 per cent of the rescue dogs showed a sufficient antibody response four months to six months postvaccination compared with 87.5 per cent of the conventionally owned dogs. There is no systematic comparison of the rabies antibody titre and protection from challenge between immunosuppressed and healthy dogs (Morters and others 2014). Many rescue dogs have poor body condition, as well as deficiencies and underlying infections which might have a negative impact on the immune response (Davlin and Vonville 2012). Still, mass vaccination campaigns in free-roaming dogs are very successful (Cleaveland and others 2006, Thiptara and others 2011, Morters and others 2014), and one study in Peru demonstrated that 97 per cent of the free-roaming dogs had antibody titre ≥0.5 IU/ml 12 months postvaccination (Chomel and others 1988). The rabies vaccines used in the present study are all inactivated and approved for the European market. If stored or administered according to the manufacturers’ instructions, they should be expected to provide a satisfactory response in the majority of dogs examined in the present study. Hence, one might question if dogs with no detectable antibody responses have been properly vaccinated before rehoming and adoption to Norway."
Sammanfattningsvis så har korrekt vaccinerade hundar har i mycket hög grad tillräckligt med antikroppar, under förutsättning att vaccinet förvarats korrekt.